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It binds the Rho antigens and does notallow them to induce antibody formation in Rhnegative individuals. Among these factors are the timeperiod of the study, the primary site of the malignancy (cervix, uterus, urethra, rectum,ovary, vulva, vagina), the histologic type of the tumor (squamous, adenocarcinoma,sarcomas, melanomas), whether the tumor is primary, persistent, or recurrent disease, andwhether exenteration is performed postsurgery, postirradiation, or both (healing is gravelyaffected by irradiation; previous surgery and irradiation are a combination for increasedmorbidity)

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Among these factors are the timeperiod of the study, the primary site of the malignancy (cervix, uterus, urethra, rectum,ovary, vulva, vagina), the histologic type of the tumor (squamous, adenocarcinoma,sarcomas, melanomas), whether the tumor is primary, persistent, or recurrent disease, andwhether exenteration is performed postsurgery, postirradiation, or both (healing is gravelyaffected by irradiation; previous surgery and irradiation are a combination for increasedmorbidity). Lower incidence of cold hands and feet, lesschances of precipitating Raynaud’s phenomenon.4

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REMsleep-related dream imagery intruding into wakefulnessmay account for VHs in some PD patients, as part of aREM sleep disorder that may include sleep-onset REMperiods in the daytime, Stage 1 REM during the night, andpost-REM delusions at night (Arnulf et al., 2000; Nomuraet al., 2003; Kulisevsky and Roldan, 2004). Thisthreshold load imposed by PEEPi may interferewith ventilator triggering requiring the patient toovercome the imposed PEEPi before the trigger tothreshold is reached.